KMID : 0377619770320010101
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Korean Jungang Medical Journal 1977 Volume.32 No. 1 p.101 ~ p.105
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Immunoglobulins and Complement C3 in Cord Blood
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Abstract
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The immunologic characteristics of newborn infants are quite different from adult, and might ¢¥be much influenced by the immunologic characteristics of their mother. In this study, immunoglobulins and complement in cord blood and venous blood of mother were determined to define the immunologic characteristics of newborn infants and the immunologic interrelationship between newborn infants and their mothers.
The concentration of IgG in cord blood of newborn infants was higher than that of their mothers and the concentration in venous cord blood was higher than in arterial cord blood. This suggests that the IgG of newborn infants is composed of not only the transfered IgG from their mothers but also the IgG produced by themselves.
The concentration of IgA in cord blood was lower than that of their mothers and IgA in arterial cord blood was more than in venous cord blood. Complement C3 in cord blood of newborn infants was lower than in their mother. Considering the concentration of C3 in venous and arterial cord blood, most of the complement of newborn infants might come from their mothers.
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